Birgid Schlindwein's

Hypermedia Glossary Of Genetic Terms

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Single nucleotide polymorphism (SNP) Sequence polymorphism differing in a single base pair.

Example for a single nucleotide substitution:
Rice cultivars with 18% or less amylose had the sequence AGTTATA at the putative leader intron 5' splice site, while all cultivars with ahigher proportion of amylose had AGGTATA.
See abstract of publication.
Related Terms:
DNA sequence The relative order of base pairs, whether in a fragment of DNA, a gene, a chromosome, or an entire genome. See base sequence.
Polymorphism Difference in DNA sequence among individuals. Applied to many situations ranging from genetic traits or disorders in a population to the variation in the sequence of DNA or proteins. Genetic variations occurring in more than 1% of a population would be considered useful polymorphisms for genetic linkage analysis. Compare mutation.
Base pair (bp) Two nitrogenous (purine or pyrimidine) bases (adenine and thymine or guanine and cytosine) held together by weak hydrogen bonds. Two strands of DNA are held together in the shape of a double helix by the bonds between base pairs. The number of base pairs is often used as a measure of length of a DNA segment, eg 500 bp.

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Programming: Herbert Maier
Database: Birgid Schlindwein. Please contact me if you encounter any mistakes or if you are missing anything
© Dr. Birgid B. Schlindwein
last update of the database 10/01/2006